Curtin University operates across an expansive network of physical campuses spanning Western Australia, regional mining hubs, and international branch locations across Asia and the Middle East. Established in 1966 as the Western Australian Institute of Technology before achieving full university status in 1987 as Curtin University of Technology, the institution delivers comprehensive programs in business, humanities, health sciences, engineering, science, and mining.

The flagship Bentley Campus serves as the university's primary academic and administrative hub. Situated six kilometers southeast of Perth's central business district, the site covers 116 hectares of landscaped grounds and suburban bushland. Bentley accommodates the majority of Curtin's academic faculties, housing major infrastructure including the multi-story TL Robertson Library, advanced engineering and innovation precinct, specialized nursing and pharmacy simulation labs, the Curtin Medical School, and the John Curtin Gallery. The site is undergoing continuous development as the "Exchange" precinct, incorporating modern student residential halls, retail hubs, commercial space, and public transit terminals. In central metropolitan Perth, the university also operates the Curtin Law School and the Curtin Graduate School of Business on Murray Street, embedding students directly within the city's financial and legal district.

Outside metropolitan Perth, Curtin maintains deep ties to Western Australia's resources sector through its regional footprints. The historic WA School of Mines campus in Kalgoorlie-Boulder, located in the Eastern Goldfields region, is a world-renowned specialized center for mining engineering, metallurgy, and geology, featuring state-of-the-art assay laboratories, underground simulator units, and student residential housing. In the South West region, Curtin co-locates learning and research infrastructure at the Margaret River Education Campus, specializing in viticulture and wine science.

Extending its footprint internationally, Curtin operates global branch campuses across five countries: Curtin Malaysia in Miri, Sarawak; Curtin Singapore in the Science Park district; Curtin Dubai in the International Academic City; Curtin Mauritius in Moka; and Curtin Colombo in Sri Lanka. Each international campus mirrors the academic framework of the Western Australian grounds, providing modern laboratories, digital library networks, and specialized student support facilities. Across all domestic and international sites, Curtin University connects industry-focused education with advanced research infrastructure.