Griffith University operates across five main campuses in South East Queensland: Nathan, Mt Gravatt, South Bank, Logan, and Gold Coast. Established in 1971 as an innovative, multi-disciplinary institution, the university delivers academic programs across business, health, humanities, science, engineering, law, education, fine arts, and performing arts.

The historic foundation site of the university is the Nathan Campus, set within 175 hectares of native bushland at the edge of Toohey Forest, roughly ten kilometers south of Brisbane's central business district. Nathan serves as a primary hub for business, environmental sciences, government, law, and engineering disciplines. Designed with environmental sustainability in mind, the site features the landmark Sir Samuel Griffith Centre—Australia's first teaching and research building powered by solar and hydrogen energy—alongside the main campus library, advanced research laboratories, multi-level sports complexes, and on-campus student residential colleges.

Adjacent to Nathan on the slopes of Toohey Forest, the Mt Gravatt Campus focuses primarily on education, criminology, and social science disciplines. Mt Gravatt provides modern teaching spaces, specialized psychology clinics, crime research centers, and comprehensive sports facilities, including an aquatic center and world-class athletics track. Connected to Nathan by short transit routes and walking trails, both southern Brisbane campuses offer an immersive, forest-surrounded learning environment.

In inner-city Brisbane, the South Bank Campus serves as the university's premier creative precinct, situated within the South Bank Cultural Centre along the Brisbane River. This urban campus brings together the Queensland Conservatorium, the Queensland College of Art and Design, the Griffith Film School, and the Australia Council for the Arts. South Bank provides industry-standard performance halls, soundstages, animation suites, art galleries, and digital design studios, embedding creative arts students directly within Queensland’s cultural quarter.

Located thirty kilometers south of Brisbane in Meadowbrook, the Logan Campus is a community-focused hub dedicated to nursing, midwifery, social work, and business education. Built around native wetlands, Logan features specialized clinical simulation wards, interactive learning spaces, and community health centers tailored to professional healthcare training.

The university's largest and fastest-growing footprint is the Gold Coast Campus, situated in Southport adjacent to the Gold Coast University Hospital. Functioning as a major center for health, medicine, dentistry, engineering, and business, this expansive modern campus features high-tech infrastructure including the multi-story Griffith Health Centre, the Advanced Engineering Building, and high-performance biomechanics laboratories. Connected directly to central Surfers Paradise and Brisbane via the G:link light rail, the Gold Coast campus delivers a fully integrated urban learning environment featuring health clinics, aquatic sports facilities, and extensive student residential villages. Across all five sites, Griffith University blends specialized academic facilities with strong transport connections across the South East Queensland corridor.